Description
- Senolytic research: disrupts FOXO4‑p53 protein‑protein interaction to trigger apoptosis of senescent cells in aging‑related pre‑clinical models.
- Chemotherapy‑induced‑injury study: investigates tissue‑function restoration after chemotoxic stress by reducing senescent‑cell burden.
- Cartilage & osteoarthritis research: explores chondrocyte senescence inhibition and SASP modulation in joint‑damage experimental systems.
- Vascular & organ senescence: applied for endothelial aging, pulmonary‑fibrosis and tissue‑microenvironment regulation pre‑clinical investigation.
